nucleic acid probes การใช้
- Nucleic acid probes can detect mutations in " rpoB " that confer rifampicin resistance.
- Hybridization assays involve labelled nucleic acid probes to identify related DNA or RNA molecules ( i . e . with significantly high degree of sequence similarity ) within a complex mixture of unlabelled nucleic acid molecules.
- "' EDANS "'( 5-( ( 2-Aminoethyl ) amino ) naphthalene-1-sulfonic acid ) is one of the most popular donors for developing FRET-based nucleic acid probes and protease substrates.
- More commonly, autoradiography is used to visualize the locations to which a radioactive substance has been transported within the body, such as cells in S phase ( undergoing DNA replication ) which incorporate tritiated thymidine, or sites to which radiolabeled nucleic acid probes bind in in situ hybridization.